Last June, Centro Hospitalar Universitário de São João started a pressurized intraperitoneal aerosol chemotherapy (PIPAC) program, having treated three patients until now.
Despite all the therapeutic advances in oncology, with remarkable survival improvements in different cancers, peritoneal metastasis (PM) continues to be a challenging field with no efficient therapeutic options, other than for a few patients with limited disease that can be candidates for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC). However, the majority will have extensive disease that prevents this strategy.

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